Streptavidin-Biotin BindingScalable ProductionCustom Biotinylation
At BOC Sciences, we provide end-to-end biotin-labeled DNA synthesis and modification services designed to meet the diverse needs of molecular biology, diagnostics, and life sciences research. By integrating advanced oligonucleotide chemistry with robust bioconjugation techniques, we can incorporate biotin labels at the 5' end, 3' end, or internal positions of DNA sequences according to your project requirements. Our expert team guarantees high-purity products with precise labeling efficiency, backed by stringent quality control measures and scalable production capabilities. With fast turnaround times and tailored support, we empower researchers, biotech companies, and diagnostic developers to accelerate innovation using reliable, ready-to-use biotinylated DNA.
Biotinylated DNA is a powerful tool because it leverages the strong biotin-streptavidin binding system, making nucleic acids easier to detect, capture, and purify. Our service helps researchers and companies solve key challenges such as:
Efficient DNA detection and hybridization assays - enhance the sensitivity and specificity of Southern/Northern blotting and in situ hybridization.
Protein-DNA interaction studies - enable accurate pull-down assays and ChIP experiments by immobilizing DNA to streptavidin beads.
Affinity purification and enrichment - isolate specific DNA molecules or DNA-binding proteins with minimal background noise.
Diagnostic probe development - create robust, biotinylated DNA probes for use in molecular diagnostics and clinical research.
Streamlined workflow - eliminate time-consuming in-house labeling, reducing experimental variability and accelerating project timelines.
Biotinylated DNA Probes
Purification & Quality Control
Scale Options
We begin by discussing your research goals, target DNA sequences, and labeling requirements (5', 3', or internal biotin).
Our experts design the optimal labeling method, selecting either chemical or enzymatic biotin incorporation.
We synthesize the DNA or oligonucleotides and perform precise biotin labeling under strict quality standards.
Products are purified by HPLC or PAGE, followed by mass spectrometry and UV analysis to confirm labeling efficiency and purity.
Final products are securely packaged and shipped, accompanied by data reports. Our team provides ongoing technical support for seamless application.
We provide fully tailored biotin labeling services, allowing modification at the 5' end, 3' end, or internally. This flexibility ensures your DNA probes, primers, or long fragments are perfectly optimized for your specific application.
Every product undergoes rigorous purification and multi-step quality checks, including HPLC, PAGE, and mass spectrometry, to guarantee high-purity DNA with reliable biotin incorporation.
Our biotinylated oligos are delivered in formats ready for use in PCR, qPCR, FISH, hybridization assays, pull-down studies, and molecular diagnostics, saving you valuable time.
From microgram-scale pilot projects to gram-scale industrial production, we offer flexible batch sizes without compromising consistency or quality, supporting both academic research and diagnostic companies.
We combine efficient workflows with dedicated technical support, ensuring rapid delivery and professional guidance to help you achieve successful results in every project.
Biotin-labeled DNA is DNA modified with a biotin tag at specific sites. It is widely used for detection, immobilization, and purification due to the strong biotin-streptavidin binding system.
We provide 5′ end, 3′ end, and internal biotin modifications, as well as enzymatic incorporation using TdT or PCR-based methods.
Common applications include hybridization assays, protein-DNA interaction studies, pull-down assays, diagnostic probe development, and molecular biology research.
All products are purified by HPLC or PAGE and undergo QC testing with mass spectrometry and UV spectrophotometry to confirm purity and labeling efficiency.
Yes, we offer flexible production scales, from small pilot studies to industrial-grade batches suitable for diagnostics and research.
Unlock the full potential of your research with our custom biotin-labeled DNA services. Whether you need high-purity probes for diagnostics, primers for PCR, or scalable DNA labeling for industrial applications, we deliver reliable results backed by expert support. Contact us today for a free consultation and quote-let's accelerate your project with precision, speed, and quality you can trust.
