As a leading service provider in the field of drug discovery and research, BOC Sciences is fully competent and dedicated to serving one-stop molecule labeling services which has be used in various detection and assay system. With the comprehensive advanced platform, BOC Sciences provides global clients with biotin labeled antibodies services to promote your research.
Both avidin and biotin can bind to proteins (including antigens, antibodies, enzymes, etc.) and fluorescein without affecting the biological activity of the latter. An antibody molecule can couple dozens of biotin or avidin molecules, and avidin or biotin molecules can bind to enzymes or fluorescein to form a biomagnification system, which can significantly improve the sensitivity of detection. Biotin is a small molecule that binds to avidin and streptavidin with very high affinity. When used in immunohistochemical techniques, the affinity of interaction makes biotin an excellent conjugate for detection. Biotin conjugates can be used in signal amplification technology. The commonly used methods are avidin biotin labeling method (LAB), avidin-biotin bridge method (BAB) and avidin-biotin peroxidase complex method (ABC).
Biotin labeling antibody technology is a technique for labeling biotin on specific antigens or antibody molecules. This enhanced amplification effect can show the properties and content of antigens or antibodies in the immune response system. It has been widely used in medical pathology, immunohistochemistry, molecular biology, biopharmaceutical and other fields of analysis and technical determination. Specifically, biotin labeled affinity purified antibodies are good for histochemical/cytochemical staining procedures and enzyme magnification immunoassay (such as microplate and membrane ELISA).
- Minimize steric hindrance between biotinylated antibodies and streptavidin
- Obtaining more stable biotin or streptavidin complex
- Leading antibody service technology
- Advanced instruments and equipment
- A professional antibody technician
- Analytical HPLC and MS analyses are performed in every development cycle.
- Full spectrum of Modification and Activation Services