BOC Sciences offers synthetic polyethylene glycol modification and bioconjugation services by site specific ligation of PEG to peptides, proteins, oligonucleotides, antibodies, lectins, enzymes, toxins, drugs or other small molecules. Our knowledge, skills and capabilities will put your project on the right track and provide an enhanced value proposition.
PEGylation is the process of covalent and non-covalent attachment or merging of polymer chains with molecules and macrostructures (such as drugs, therapeutic proteins, or vesicles). PEG polymers have many inherent good biological properties, including high water solubility and lack of toxicity, immunogenicity and antigenicity. Therefore, in many applications, the chemical modification of bioactive compounds, such as peptides, antibody fragments, enzymes or small molecules with polyethylene glycol chain, so called PEGylation, usually leads to improved pharmacokinetics and biological function.
PEGylation technology has evolved for decades since 1970s and has been successfully used for marketed therapeutic solutions. Over 10 PEGylated biotherapeutics have been approved in the United States and Europe.
With years of experience in bioconjugation services, BOC Sciences provides a full spectrum of quality solutions, from single reagents to comprehensive PEGylation service, to meet your specific needs.
