At BOC Sciences, we specialize in providing comprehensive peptide conjugation services tailored to meet your specific research and development needs. With our expertise in bioconjugation chemistry and state-of-the-art facilities, we offer a wide range of conjugation options to modify peptides for various applications in drug delivery, diagnostics, and biotechnology.
We provide a comprehensive range of peptide conjugation services for various applications, including diagnostic assays, drug therapy, imaging, nucleic acid delivery, and affinity chromatography. Our service portfolios encompass a diverse array of peptide conjugates, including enzyme conjugates, antibody conjugates, nanoparticle conjugates, DNA/RNA-peptide conjugates, drug-peptide conjugates, and more.
We offer conjugation of peptides with a variety of immunogenic carrier proteins, including Keyhole Limpet Hemocyanin (KLH), Diphtheria Toxoid, and others. These conjugates can be utilized as immunogens or for affinity purification in research and diagnostic assays.
Our peptide-drug conjugation services enable the covalent attachment of therapeutic agents such as drugs, biologics, or toxins to peptide delivery vectors. We specialize in conjugating drugs with short delivery vectors, including cell-penetrating peptides (CPPs), for targeted drug delivery applications.
We offer coupling of peptides with various molecules, including enzymes, oligonucleotides, and small molecules, to enhance their properties for specific applications.
Peptide bioconjugation refers to the process of linking peptides to other biomolecules or synthetic compounds to create multifunctional conjugates with diverse applications. This process often involves the use of cross-linking reagents or reactive functional groups to facilitate the covalent attachment of peptides to target molecules. Bioconjugation techniques enable the creation of peptide-drug conjugates for targeted drug delivery, peptide-antibody conjugates for diagnostic assays, and peptide-nanoparticle conjugates for imaging and therapeutic applications.
In addition to peptide conjugation, we offer a wide range of peptide modification services, including labeling with fluorescent or enzymatic substrates, attachment of tags or labels, and incorporation of post-translational modifications (PTMs). BOC Sciences' custom peptide modification services allow for precise control over peptide characteristics and functionalities tailored to your specific requirements.
Peptide modification involves the chemical or enzymatic alteration of peptides to introduce specific functionalities or enhance their properties. Common modifications include the addition of fluorophores, chromophores, or other labels for imaging and detection purposes, as well as the incorporation of post-translational modifications (PTMs) to mimic natural peptide structures. Our expertise extends to the synthesis of modified peptides with precise modifications tailored to your requirements, including C-terminal modifications, N-terminal modifications, peptide cyclization, backbone modifications, labeling/conjugation.
Peptide conjugation with immunogenic carrier proteins, including Keyhole Limpet Hemocyanin (KLH) and Diphtheria Toxoid, facilitates the generation of immunogens for antibody production. These conjugates can also be used in affinity purification to isolate specific antibodies for research or diagnostic purposes.
Peptide-drug conjugation offers a promising approach for targeted drug delivery. By conjugating therapeutic agents with peptide delivery vectors, such as cell-penetrating peptides (CPPs), researchers can enhance drug uptake and specificity, potentially reducing off-target effects and improving therapeutic outcomes.
Peptide conjugation plays a vital role in diagnostic assays by enabling the immobilization of peptides onto surfaces or carriers for the detection of specific biomolecules. These conjugates can be labeled with fluorescent, chemiluminescent, or chromogenic substrates to facilitate sensitive and specific detection in various diagnostic platforms.
Peptide conjugates serve as valuable research tools for studying protein-protein interactions, gene regulation, and cellular signaling pathways. By conjugating peptides with nucleic acids, enzymes, or nanoparticles, researchers can develop innovative tools for studying complex biological processes with high precision.
By conjugating peptides to various detection labels, such as fluorescent or chemiluminescent markers, peptide conjugation significantly enhances the sensitivity and specificity of diagnostic assays. This modification allows for more precise and reliable detection of target biomolecules, improving the performance of diagnostic tests.
Conjugating peptides to nanoparticles can significantly enhance their stability, bioavailability, and ability to bind to specific biological targets. This combination is particularly useful in imaging, biosensing, and delivering molecular payloads, enabling more targeted interactions and improved functionality for research and analytical purposes.
Peptide conjugation can be achieved through various methods, such as N-terminal amine labeling, C-terminal acid labeling, and the use of functional groups like thiols or click chemistry. Each method allows for precise attachment to a variety of molecules, facilitating the creation of multifunctional conjugates for a wide range of applications.
