As a leading CRO, BOC Sciences specializes in offering top-notch bioconjugation services that cater to drug discovery and drug delivery. Our team of highly skilled scientists possesses vast expertise in an extensive range of bioconjugation techniques. Whether it's traditional cross-linking methods or click chemistry approaches, we have the proficiency to apply the most appropriate technique based on the unique requirements of each project. We invest in advanced spectrometers, chromatography systems, and other analytical instruments, ensuring accurate characterization and validation of bioconjugates.
Bioconjugation is the process of linking two or more biomolecules together, often involving the covalent attachment of synthetic molecules to biological entities. These biomolecules can include proteins, antibodies, enzymes, nucleic acids, and more. The result is a bioconjugate, a novel hybrid entity with properties distinct from its individual components. Bioconjugation enables the introduction of desirable attributes, such as increased stability, targeted specificity, and enhanced bioactivity.
We understand that each research project is unique, and therefore, we offer customized solutions tailored to your specific objectives. Our team works closely with you to comprehend your research goals, design an optimal bioconjugation strategy. We take pride in our flexibility to accommodate various biomolecule types, conjugation chemistries, and project complexities. Our bioconjugation services include:
We set up and operate a Good Manufacturing Practice (GMP) bioconjugation service, adherence to strict regulatory guidelines, and a commitment to quality and safety. Our GMP bioconjugation capabilities include regulatory compliance, personnel training and qualification, SOP development, equipment and instruments, raw materials and quality control, process validation, quality assurance and quality control, documentation and record keeping, facility audits and inspections, and continuous improvement.
Biotin is a small molecule that forms an extremely stable and specific interaction with streptavidin.
Genetic engineering techniques allow the fusion of specific peptide tags or functional proteins to the target biomolecule during its expression in cells or organisms.
Chelating agents, such as EDTA or DTPA, can be conjugated to biomolecules and subsequently complex with metal ions, enabling various applications in imaging and diagnostics.
Hydrophobic molecules can be inserted into lipid membranes or hydrophobic pockets of proteins to achieve bioconjugation.
We employ a variety of methods for characterizing and validating the success of bioconjugation reactions. Our comprehensive bioconjugation platform enable us to assess the efficiency of conjugation, determine the stoichiometry of the bioconjugate, and ensure the integrity and functionality of the resulting product.
Our bioconjugation services serve a wide range of clients in drug conjugates, drug discovery, and various other areas of research and industry.
Why Choose BOC Sciences's Bioconjugation?
