Stable Isotope Labeling of Carbohydrates

* Please kindly note that our services can only be used to support research purposes (Not for clinical use).

BOC Sciences provides our global customers with a range of high-quality stable isotope labeling services for biomedical research. Based on extensive experience and advanced technology, we are able to work closely with customers to design and manufacture customized and customized product binding projects. BOC Sciences can provide custom carbohydrates labeled with stable isotopes including 2H (deuterium), 15N, 13C, or a combination of 15N and 13C.  

Introduction

As a unique tracer, stable isotope labeled compounds and their derivatives play an irreplaceable role in many research and application fields. A variety of stable isotope labeled compounds and their derivatives are needed in the fields of medicine, agriculture, environment, geology and medical diagnosis. Carbohydrates compounds labeled with stable isotopes maintain physical and chemical properties, allowing consistent interactions in biochemical pathways. Labelled products closely mimic natural metabolites, allowing accurate metabolic measurements without introducing increased experimental noise. The method is suitable for cells and higher organisms from insects to mammals.

Application

Through the study of naturally occurring isotopes, the use of stable isotopes in the study has been well established. Migration patterns of land-based and water-based species are tracked using isotope ratios unique to individual feeding areas. The spread of bacteria can also be tracked using natural isotope ratios in the host food source. Just as natural compounds containing large amounts of stable isotopes are not harmful to organisms, artificially labeled compounds can also be used without changing physiological or biochemical functions.

Advantages

  • Deep knowledge and rich experience in biomaterial modification and conjugation
  • Strict purification and characterization.
  • Can contain any amino acid residue.
  • It has stable 13C and 15N isotopes, which can replace 12C and 14N selected by customers.
  • All samples are carefully monitored for stability and characterized to ensure batch to batch consistency.
  • Cost-Effectiveness and High Efficiency.

Project Workflow

Project Workflow

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