Biotinylation for RNA Analysis Advanced miRNA Research Tools
At our facility, we offer custom biotinylated miRNA services with a focus on quality and tailored to your specific requirements. Our state-of-the-art technology allows us to biotinylate miRNA sequences in a customized manner, enhancing your RNA-based assays. Biotinylated miRNA enables researchers to more easily detect, isolate, and analyze these small RNA molecules. It has applications in gene expression analysis, RNA-protein interaction studies, and functional genomics, among others.
Biotinylated miRNA are microRNA (miRNA) molecules that have been modified to include biotin, a small molecule commonly used for labelling. Biotin is a vitamin (vitamin B7) that has a strong affinity for proteins like streptavidin or avidin, which are often used in research to capture or detect biotinylated molecules.
Biotinylated miRNA is a versatile tool in RNA research, helping scientists investigate miRNA functions, interactions, and their role in gene expression regulation.
The strong binding affinity between biotin and streptavidin provides a highly sensitive and reliable detection system.
Biotinylated miRNA can be captured using streptavidin-coated beads, simplifying the isolation process for further analysis.
This technique is widely used in molecular biology, biotechnology, and medical research.
Our Biotinylated miRNA Services range is designed to cater to a wide range of RNA-based research and application needs, utilizing the most advanced protocols and custom options to ensure exceptional service. Whether you are exploring RNA-based therapeutics, studying gene expression, or looking to modify genes for basic research, our team is equipped with the facilities and expertise to meet your biotinylated miRNA requirements.
Custom Biotinylation of miRNAWe provide custom biotinylation services for synthetic or endogenous miRNA molecules. Our custom biotinylation process is designed to ensure high efficiency with minimal alteration to the native structure of the miRNA, making it suitable for downstream applications such as miRNA profiling and gene regulation studies.
miRNA Detection and QuantificationOur service includes the provision of biotinylated miRNA for highly sensitive detection and quantification using streptavidin-based assays such as ELISA, qPCR, or fluorescence assays. We can customize our service to precisely measure the levels and activity of miRNAs in various biological samples.
miRNA-Protein Interaction StudiesWe can use our biotinylated miRNA in RNA-protein interaction studies to investigate the binding of miRNAs to their target proteins. Our service helps researchers gain insights into the mechanisms of gene silencing and miRNA regulation.
RNA Capture and IsolationOur biotinylated miRNA can be used for efficient RNA capture using streptavidin-coated beads. Our service streamlines the isolation process, allowing for easy and clean separation of miRNAs for downstream analyses such as sequencing, northern blotting, or hybridization studies.
miRNA Target Interaction ScreeningWe provide biotinylated miRNA for high-throughput screening of miRNA-target interactions. Our service facilitates the identification and validation of miRNA target genes in various biological systems using biotinylation.
miRNA Functional Genomics StudiesWe offer support for functional genomics studies by providing biotinylated miRNA for gene expression modulation. Our service enables researchers to investigate the effects of miRNAs on gene expression and cellular processes.
Custom SolutionsWe understand that time is of the essence in research, which is why our biotinylated miRNA services are designed for fast turnaround without compromising quality. We also offer custom solutions tailored to your specific experimental needs.
Quality Control and AssuranceOur quality control processes for every batch of biotinylated miRNA ensure that the biotinylation process does not affect miRNA activity. We provide detailed reports on the integrity and purity of the final product.
Contact us with your research project's requirements: whether you want synthetic or endogenous miRNA, how you plan to use it (gene regulation, protein interaction studies, etc. ), and the specific biotinylation protocol or custom requirements you might have. We will consult with you during this stage to select the best protocol for your research.
Our team will then move on to biotinylate your miRNA. Using advanced techniques, we modify your miRNA with biotin such that it is not hindered in activity or function, retaining its original ability to bind to and affect mRNA or protein targets.
Each batch of biotinylated miRNA is tested for purity, integrity, and function. We employ techniques like gel electrophoresis, quantitative PCR (qPCR), and streptavidin-based assays to ensure that the biotinylated miRNA is of the highest quality and ready for your research application.
Once the biotinylated miRNA passes quality control, it is packaged carefully and sent to you. Detailed documentation is provided, including the miRNA's purity report, biotinylation efficiency, and suggested protocols for your specific application.
We offer ongoing technical support for your project, including troubleshooting, experimental design consultation, and advice on best practices for using biotinylated miRNA in your research.
We use state-of-the-art protocols to ensure optimal biotinylation, maintaining the integrity and functionality of the miRNA.
Ideal for applications in RNA capture assays, miRNA profiling, and miRNA-target interaction studies.
Our team delivers high-quality biotinylated miRNA within short timelines, helping you move your research forward efficiently.
We offer tailored services to suit the specific needs of your project, whether you're working with synthetic miRNA or endogenous miRNA.
The biotin group allows the miRNA to be easily detected using streptavidin-based assays (such as ELISA, western blotting, or fluorescence microscopy). Streptavidin, which binds tightly to biotin, can be used to capture the biotinylated miRNA for subsequent analysis.
The biotinylation of miRNA can be used to study interactions between miRNA and other proteins or nucleic acids, which is important for understanding the regulatory role of miRNAs in cellular processes.
Researchers can use biotinylated miRNA to investigate miRNA-target interactions, allowing for more accurate and efficient studies on gene regulation.
We conduct rigorous quality control at every stage of the process. This includes purity testing, biotinylation efficiency, and functional validation to ensure that the biotinylated miRNA retains its biological activity. We provide detailed reports with each order.
Yes, biotinylated miRNA is ideal for high-throughput screening of miRNA-target interactions. It can be used in large-scale studies to identify and validate miRNA targets efficiently.
Absolutely! We offer ongoing technical support to help you with any questions or troubleshooting related to the use of biotinylated miRNA in your experiments. Our team is available to assist with protocol optimization and data interpretation.
