Oligonucleotide Bioconjugation

* Please kindly note that our services can only be used to support research purposes (Not for clinical use).

BOC Sciences provides customized nucleic acid and oligonucleotide coupling reagents as detection tools or therapeutic agents for DNA detection. As a leading service provider in the field of drug discovery and research, our nucleic acid and oligonucleotide conjugation service chemically modifies nucleic acids at individual nucleotides or at specific sites within oligonucleotides.


Since it has been observed that synthetic oligonucleotides and their modified analogues can successfully regulate the function of specific genes, the study of 1p2 oligonucleotide therapy has been strengthened. It is believed that oligonucleotide-based therapy will become a reality in the future. The role of chemists in oligonucleotide science has become much more demanding. Chemists have designed and synthesized oligonucleotides that have been modified in different parts of the sequence. Biologists have evaluated their biological significance of inhibiting gene function as antisense, antigene or aptamer.


Oligonucleotide bioconjugation services have been widely used in detection development, such as hybridization testing, FISH, ChIP testing, cell imaging, in vivo imaging and homogenous DNA detection. Drugs based on oligonucleotides have the potential to treat or cure almost all diseases and are one of the key categories of therapeutic drugs in the future. Biological conjugated oligonucleotides are a subset of this class, which have emerged from basic research and have been successfully translated into clinical practice.

Our Advantages

  • Extensive oligonucleotide bioconjugation Strategy
  • Cross-linking at a specific location
  • Well-trained biological and organic chemists
  • Strict quality control process
  • Data analysis & report delivery
  • 24h-available customer service

Project Workflow

Oligonucleotide Bioconjugation

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