- Liposome Conjugation
- Stable Isotope Labeling
- Glycan Conjugation
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Drug Conjugation Services
- Peptide-Drug Conjugation (PDC)
- Aptamer-Drug Conjugation (ApDC)
- Antibody-siRNA Conjugation (ARC)
- Antibody Cell Conjugation (ACC)
- Virus-like Drug Conjugation (VDC)
- Immune-Stimulating Antibody Conjugation (ISAC)
- Antibody-Exotoxin Conjugation (AExC)
- Antibody-Photosensitizer Conjugation (APC)
- Antibody-Biopolymer Conjugation (ABC)
- Fragment-Drug Conjugation (FDC)
- Protein-Antibody Conjugation (PAC)
- Antibody-Drug Conjugation
- Protein-Drug Conjugation
- Small Molecule Ligand-Drug Conjugation
- Peptide RNA Conjugation
- Antibody-PNA Conjugation
- Peptide-PNA Conjugation
- Protein-PNA Conjugation
- GalNAc-siRNA Conjugation
- Degrader-Antibody Conjugation (DAC)
- Hapten-Carrier Conjugation
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Custom Bioconjugation Services
- Antibody Conjugation Services
- Protein/Peptide Crosslinking
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Oligonucleotide Bioconjugation
- Carbohydrate-Oligonucleotide Conjugation
- PEG Conjugated Oligonucleotide
- Antibody Oligonucleotide Conjugation
- Peptide Oligonucleotide Conjugation
- Enzyme Labeling of Oligonucleotides
- Gold Nanoparticles labeled Oligonucleotide
- Biotin Labeled Oligonucleotides
- Fluorescence Labeling of Oligonucleotides
- Protein Oligonucleotide Conjugation
- Oligonucleotide-Loaded Lipid Nanoparticle
- Oligonucleotides Conjugated with Small Molecules
- Oligonucleotide Liposome Conjugation
- Additional Conjugation Services
- Cholesterol Conjugation
- Peptide Conjugation Services
- Enzyme Labeling
- PEGylation
- Biotinylation
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Fluorescence Labeling
- Fluorescence Labeling of Peptides
- Fluorescence Labeling of Oligonucleotides
- Fluorescence Labeling of Antibody
- Fluorescence Labeling of Proteins
- Fluorescence Labeling of Nucleic Acids
- Fluorescence Labeling Polysaccharide
- Fluorescence Labeling of Enzyme
- Fluorescence Labeling Carbohydrate
- Fluorescence Labeling Fatty Acid
- Fluorescence Labeling of Magnetic Nanoparticles
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Nanoparticles & Beads Conjugation
- Gold Nanoparticles labeled Oligonucleotide
- Gold Nanoparticles labeled DNA
- Gold Nanoparticles labeled RNA
- Gold Nanoparticles labeled Streptavidin
- Gold Nanoparticles labeled Antibody
- Gold Nanoparticles labeled Peptides
- Gold Nanoparticles labeled Lectin
- Gold Nanoparticles labeled Protein
- Magnetic Beads labeled Antibody
- Silver Nanoparticles Labeled Antibody
- Silver Nanoparticles Labeled Streptavidin
- Magnetic Beads labeled Protein
- Luminex Bead Labeled Antibody
- Luminex Bead Labeled DNA
- cGMP Bioconjugation Manufacturing
Enzymatic Crosslinking Services
The ability of enzymes to promote the formation of covalent cross-linking between protein amino acid residues provides a variety of possibilities for protein modification, which complements the limitations of chemical cross-linking methodology. As a leading service provider in the field of drug discovery and research, we provide a majority of enzymatic crosslinking services.
Introduction
Despite the wide commercial availability, reaction efficiency and versatility of chemical cross-linking agents, their applications in food processing and tissue engineering are particularly disadvantageous because many of these compounds are rated as toxic or may form harmful by-products leached from the cross-linked protein matrix. In order to overcome these limitations, much attention has been paid to the study of enzymes that catalyze the formation of protein cross-links in vitro. This allows site-directed coupling of proteins with different properties and ab initio assembly of polymerized protein networks. Transferase, hydrolase and redox enzyme can be used as catalysts for the synthesis of cross-linked proteins, thus complementing the chemical cross-linking strategy.
Application
In various application fields that require biological protein matrix with similar structural and mechanical properties, the method of covalent assembly of proteins into macromolecular networks by enzyme catalysis has been widely studied. For example, the ability of enzymes to form cross-linked protein networks has been used to change the texture and appearance of foods, to develop new biomimetic tissue scaffolds or to enhance protein-based fibers for textile manufacturing.
Our Advantages
- Provide a variety of possibilities for protein modification
- Extensive Enzymatic Crosslinking Strategy
- High specificity and minimal side effects.
- Cross-linking at a specific location
- Well-trained biological and organic chemists
- Guaranteed Quality
- Data analysis & report delivery
- 24h-available customer service
Project Workflow
