High-Affinity Binding System High-Sensitivity Immunoassay Expert Bioconjugation Support
At BOC Sciences, we offer high-precision antibody-streptavidin conjugation services that harness the unparalleled affinity of the biotin-streptavidin system to deliver highly sensitive and specific detection tools for research and diagnostics. Using optimized chemistries and controlled reaction conditions, our experts ensure that every conjugate maintains native antibody functionality while achieving superior binding performance. Whether you require HRP-labeled antibodies for colorimetric ELISA, fluorescent streptavidin conjugates for imaging, or customized biotin-streptavidin complexes for biosensor development, we provide turnkey, validated, and ready-to-use solutions that improve signal strength, reproducibility, and overall assay sensitivity.
Inconsistent labeling performance: We eliminate variability by using optimized molar ratios and controlled conjugation kinetics.
Loss of antibody activity: Our mild conjugation chemistries preserve antibody structure and binding sites.
Weak signal or high background: We deliver conjugates with optimized stoichiometry to enhance detection sensitivity while minimizing nonspecific binding.
Limited assay flexibility: Our customizable platforms allow integration with diverse reporters-enzymatic, fluorescent, or nanoparticle-based.
Time and cost inefficiency: Outsourcing to our specialists saves you the labor and uncertainty of in-house conjugation while ensuring reproducible, validated results.
Custom Streptavidin Conjugation
Antibody Biotinylation and Validation
Fluorescent and Enzymatic Streptavidin Labeling
Assay-Ready Conjugate Formulations
End-to-End Technical Consultation and Support
We begin with a detailed discussion to understand your research goals, target antibody characteristics, and downstream applications. Our scientists evaluate your specifications—antibody format, required label type, detection platform—to design the optimal conjugation strategy.
Based on antibody structure and application, we select the most suitable coupling chemistry (e.g., NHS-ester, maleimide, click chemistry, or enzymatic biotinylation). Each reaction plan includes stoichiometric balancing to maintain antibody activity.
The conjugation is performed under controlled conditions to ensure reproducibility and high yield. Post-reaction, conjugates are purified using size-exclusion or affinity chromatography to remove excess reagents and free streptavidin.
Every conjugate undergoes rigorous QC testing—including protein concentration, biotin ratio, SDS-PAGE purity, and functional assay verification—to confirm consistency and binding efficiency.
Final conjugates are formulated in assay-compatible storage buffers and delivered in lyophilized or liquid form, accompanied by a detailed Certificate of Analysis (CoA) and technical datasheet.
Our scientific team provides ongoing support for implementation, assay optimization, and troubleshooting to ensure your conjugates perform optimally across all applications.
Our optimized reaction kinetics and controlled conjugation environment ensure maximum labeling efficiency with minimal loss of antibody functionality. This translates into higher signal strength and improved reproducibility across assays.
By fine-tuning the streptavidin-to-antibody ratio, we achieve superior signal-to-noise performance-ideal for ELISA, IHC, and fluorescent detection systems requiring ultra-low background.
We offer flexible, tailor-made conjugation designs, including enzyme, fluorophore, or nanoparticle labels. Each project is adapted to your experimental setup, sample type, and detection platform for optimal results.
Each production batch undergoes comprehensive QC validation—purity testing, activity assay, and structural confirmation—to guarantee consistent quality, batch-to-batch stability, and regulatory traceability.
With standardized workflows and in-house conjugation platforms, we ensure rapid delivery times for research-grade or production-scale orders without compromising quality.
Our team of experienced biochemists and assay developers provides end-to-end technical guidance, helping you choose the right conjugation chemistry, troubleshoot assay conditions, and optimize detection performance.
Most IgG, IgM, and recombinant antibody formats can be successfully conjugated, including monoclonal and polyclonal antibodies. Our team assesses molecular characteristics to determine the best coupling approach.
No. We use optimized, mild conjugation chemistries to preserve epitope integrity and maintain full antigen-binding activity. Each conjugate is validated through activity assays before delivery.
We provide enzymatic (HRP, AP) and fluorescent (FITC, PE, Alexa Fluor, quantum dots) streptavidin conjugates. Custom labels can also be added based on detection needs.
Yes. Each order is delivered with a Certificate of Analysis (CoA) summarizing purity, conjugation ratio, and QC test results, ensuring full transparency and traceability.
Partner with BOC Sciences for precise, reproducible, and application-validated conjugation solutions tailored to your research or diagnostic needs. Our scientific experts are here to guide you through every stage - from project design to successful implementation. Contact us today to discuss your project, request a quote, or schedule a free technical consultation. Experience how expert-engineered conjugation can transform your detection performance and research outcomes.
